Dallas Voice (Dallas, Tex.), Vol. 33, No. 32, Ed. 1 Friday, December 16, 2016 Page: 2 of 48
forty eight pages : ill.View a full description of this newspaper.
Extracted Text
The following text was automatically extracted from the image on this page using optical character recognition software:
TRIUMEQ is a once-a-day pill used to treat HIV-1. In some people, TRIUMEQ should not be used by itself. Take TRIUMEQ exactly
as your healthcare provider tells you.
APPROVED USES
TRIUMEQ is a prescription HIV-1 (Human Immunodeficiency Virus-type 1) medicine used alone or with other antiretroviral medicines to treat HIV-1 infection in adults. HIV-1 is the virus that causes
AIDS. TRIUMEQ is not for use by itself in people who have or have had resistance to abacavir, dolutegravir, or lamivudine. TRIUMEQ should not be used in children under the age of 18.
TRIUMEQ does not cure HIV-1 or AIDS. You must keep taking HIV-1 medicines to control HIV-1 infection and decrease HIV-related illnesses.
IMPORTANT SAFETY INFORMATION
What is the most important information I should know about TRIUMEQ?
TRIUMEQ can cause serious side effects, including:
• Serious allergic reactions (hypersensitivity reaction) that can cause death have happened
with TRIUMEQ and other abacavir-containing products. Your risk of this allergic reaction to
abacavir is much higher if you have a gene variation called HLA-B*5701. Your healthcare
provider can determine with a blood test if you have this gene variation. If you get symptoms
from 2 or more of the following groups while taking TRIUMEQ, call your healthcare
provider right away: 1. fever; 2. rash; 3. nausea, vomiting, diarrhea, or stomach pain;
4. generally ill feeling, extreme tiredness, or achiness; 5. shortness of breath, cough,
or sore throat. Your pharmacist will give you a Warning Card with a list of these symptoms.
Carry this Warning Card with you at all times.
If you stop taking TRIUMEQ because of an allergic reaction, never take TRIUMEQ or
any other abacavir- ordolutegravir-containing medicines again. If you take TRIUMEQ or
any other abacavir-containing medicine again after you have had an allergic reaction, within
hours you may get life-threatening symptoms that may include very low blood pressure or
death. If you stop TRIUMEQ for any other reason, even for a few days, and you are not allergic
to TRIUMEQ, talk with your healthcare provider before taking it again. Taking TRIUMEQ again
can cause a serious allergic or life-threatening reaction, even if you never had an allergic
reaction to it before Ifyour healthcare provider tells you that you can take TRIUMEQ
again, start taking it when you are around medical help or people who can call a
healthcare provider if you need one.
• A buildup of acid in your blood (lactic acidosis). Lactic acidosis can happen in some people
who take TRIUMEQ. This serious medical emergency can cause death. Call your healthcare
provider right away if you feel very weak or tired; have unusual muscle pain; have trouble
breathing; have stomach pain with nausea and vomiting; feel cold, especially in your arms and
legs; feel dizzy/light-headed; or have a fast/irregular heartbeat.
• Serious liver problems can happen in people who take TRIUMEQ. In some cases, these
serious liver problems can lead to death. You may be more likely to get lactic acidosis or
serious liver problems if you are female, very overweight (obese), or have been taking
nucleoside analogue medicines for a long time. Call your healthcare provider right
away if you get any of the following signs or symptoms:
oyellow skin, or the white part of the eyes turns yellow (jaundice); dark urine; light-colored
stools; loss of appetite for several days or longer; nausea; pain, aching, or tenderness on the
right side of your stomach area
• Worsening of hepatitis B virus in people who have HIV-1 infection. If you have HIV-1
and hepatitis B virus (HBV), your HBV may get worse (flare-up) if you stop taking TRIUMEQ.
A "flare-up" is when your HBV suddenly returns in a worse way than before. Worsening liver
disease can be serious and may lead to death. Do not stop taking TRIUMEQ without first talking
to your healthcare provider, so he or she can monitor your health.
• Resistant hepatitis B virus. If you have HIV-1 and hepatitis B, the hepatitis B virus can change
(mutate) during your treatment with TRIUMEQ and become harder to treat (resistant).
• Use with interferon and ribavirin-based regimens. If you're taking TRIUMEQ and
interferon, with or without ribavirin, tell your healthcare provider about any new symptoms.
Worsening of liver disease that has caused death has happened in people infected with both
HIV-1 and hepatitis C who were taking antiretroviral medicines and interferon.
Who should not take TRIUMEQ?
• Do not take TRIUMEQ if you:
o have the HLA-B*5701 gene variation
oare allergic to abacavir, dolutegravir, or any of the ingredients in TRIUMEQ
otakedofetilide (Tikosyn®)
ohave liver or kidney problems
What are other possible side effects of TRIUMEQ?
• People with a history of hepatitis B or C virus may have an increased risk of developing new
or worsening changes in certain liver tests during treatment with TRIUMEQ. Your healthcare
provider may do tests to check your liver function before and during treatment with TRIUMEQ.
• When you start taking HIV-1 medicines, your immune system may get stronger and begin
to fight infections that have been hidden in your body for a long time. Tell your healthcare
provider right away if you start having new symptoms after you start taking TRIUMEQ.
• Changes in body fat can happen in people who take HIV-1 medicines.
• Some HIV-1 medicines, including TRIUMEQ, may increase your risk of heart attack.
The most common side effects of TRIUMEQ include: trouble sleeping, headache, tiredness
These are not all the possible side effects of TRIUMEQ. Tell your healthcare provider if you have
any side effect that bothers you or that does not go away.
What should I tell my healthcare provider before taking TRIUMEQ?
• Before you take TRIUMEQ, tell your healthcare provider if you:
o have been tested and know whether or not you have a gene variation called HLA-B*5701
o have or have had liver problems, including hepatitis B or C infection; have kidney problems;
have heart problems, smoke, or have diseases that increase your risk of heart disease such
as high blood pressure, high cholesterol, or diabetes; drink alcohol or take medicines that
contain alcohol
oare pregnant or plan to become pregnant. It is not known if TRIUMEQ will harm your
unborn baby
oare breastfeeding or plan to breastfeed. Do not breastfeed if you take TRIUMEQ
• You should not take TRIUMEQ if you also take:
oabacavir (EPZICOM® TRIZIVIR? or ZIAGEN®)
o lamivudine (COMBIVIR? Dutrebis™, EPIVIR? EPIVIR-HBV? EPZICOM,
or TRIZIVIR)
oemtricitabine (Emtriva? Atripla? Complera? Stribild? or Truvada®)
Important Safety Information continued on next page
©2016 ViiV Healthcare group of companies. All rights reserved.
Printed in USA. 723601RO August 2016
Healthcare
If you don't have prescription
coverage and can't afford your medicines,
visit ViiVHeglthcareForYou.com or call the
ViiV Healthcare Response Center
1-877-844-8872
ViiV YOU
Upcoming Pages
Here’s what’s next.
Search Inside
This issue can be searched. Note: Results may vary based on the legibility of text within the document.
Tools / Downloads
Get a copy of this page or view the extracted text.
Citing and Sharing
Basic information for referencing this web page. We also provide extended guidance on usage rights, references, copying or embedding.
Reference the current page of this Newspaper.
Nash, Tammye. Dallas Voice (Dallas, Tex.), Vol. 33, No. 32, Ed. 1 Friday, December 16, 2016, newspaper, December 16, 2016; Dallas, Texas. (https://texashistory.unt.edu/ark:/67531/metapth1007223/m1/2/: accessed July 12, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu.; crediting UNT Libraries Special Collections.