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July 15, 1938 Dr. F. B. Peak 11$ Litty and Caopany Indianapols , Indiana My dear Dr. Peck: You will recall our conversation at San Fran- cisco regarding placental extracts. As I indicated, it ould be very desirable to have two preparation; one derived froe the fetal portion, tie other from the maternal portion of the placenta. Perhaps hog placenta would afford the best chance for relative separat ion On the b-sis of prelibinar studies, t sees to me th t the maintenance of te e'rum oalcitm concentration at different levels on th two sides of the placental barrier ay be dependent on the existence of two distinct factors in the placenta: (1) a calcium depressing substance in the decidua4 (2) a calcium elevating substance in the fetal part of t. placenta. If this could be uneqluivically demonstrated, the findings, in my opinion, would be of funda- mental importance. Any assistance or suggestions that you iay have to offer will be gratefully received. Sincerely yours, . Bodansky, M D. M El